Centreville is an incorporated town in Queen Anne's County, Maryland, United States. Incorporated in 1794, it is the county seat of Queen Anne's County. The population was 4,285 at the 2010 census. The ZIP code is 21617 and the area code is 410. The local telephone exchange is 758. It hosts the Queen Anne's County Fair each summer and was home to three franchises during the existence of the Eastern Shore Baseball League -- the Colts, Red Sox, and Orioles. The book Red Kayak by Priscilla Cummings is set in Centreville.